🧪 Protocols.io Bridge
Search, browse, and retrieve scientific protocols from protocols.io via REST API. Client token authentication
Browse reusable instructions for your AI tools. Copy and customize a prompt, or download a skill for a supported agent.

Search, browse, and retrieve scientific protocols from protocols.io via REST API. Client token authentication
Classify germline variants from VCF/BCF files according to the ACMG/AMP 2015 28-criteria evidence framework and
Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs
Medication photo to personalised PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance
Search PubMed for a gene name or disease term and generate a structured research briefing of the top recent English-language
Detect Neanderthal and Denisovan introgression segments from modern human genomes
Deterministic CRISPR screen hit ranking from local guide-level count tables
Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast
Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.
Compute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.
Local scVI/scANVI-based single-cell latent embedding and batch-aware integration from raw-count .h5ad or 10x
Aggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into
Two-sample Mendelian Randomisation from GWAS summary statistics with IVW, MR-Egger, weighted median/mode, and
Fetch a region of GWAS summary statistics from the NHGRI-EBI GWAS Catalog harmonised collection via tabix-on-FTP. Use when an agent needs GWAS beta / SE / p-value for every variant in a window for one specific study (GCST accession). Input: accession, chromosome, start, end. Output: harmonised TS...
Ancestry decomposition PCA against the Simons Genome Diversity Project
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots,
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ),
Fetch a region of cis-eQTL summary statistics from EBI eQTL Catalogue v7+ via tabix-on-FTP. Use when an agent needs eQTL beta / SE / p-value for every variant in a window around a gene's TSS for one specific dataset (study × tissue × quantification method). Input: dataset_id, chromosome, start, e...
Wrapper skill for running nf-core/rnaseq bulk RNA-seq preprocessing from FASTQ or BAM inputs with strict preflight, reproducibility outputs, and downstream handoff to ClawBio bulk RNA-seq DE skills.
Wrapper skill for running nf-core/scrnaseq upstream single-cell RNA-seq preprocessing from FASTQ with strict preflight, reproducibility outputs, and downstream handoff to ClawBio scRNA skills.
Differential expression analysis for label-free quantitative (LFQ) intensity data with standard MaxQuant and
Summarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-ready
Automated sequencing quality control and advanced visualization wrapping FastQC, MultiQC, and custom chart generation. Exposes an MCP stdio server for live AI integration alongside a ClawBio CLI runner.
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