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Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis
Compute organ-specific biological age from Olink proteomic data using Goeminne et al. (2025) elastic net aging
End-to-end GWAS automation wrapping PLINK2 for genotype QC and REGENIE for two-step whole-genome regression association
Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture
Deterministic marker-dominance region mapping from local spot-count CSVs
Deterministic multi-sample QC triage for identity, sex, contamination, and batch-shift outliers
Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein, ancestry) measurement. Use when an agent needs per-variant beta / SE / p-value around a coloc-lead variant for downstream colocalisation, Mend...
Build, query, and analyse biomedical knowledge graphs in TuringDB, a columnar graph database with git-like versioning.
Render a 4-panel regional LocusCompare diagnostic for one (lead variant, exposure study, outcome study) tuple - overlays GWAS Manhattan, QTL Manhattan, GENCODE gene track, and cross-trait scatter colored by LD r². Use when an agent needs visual confirmation that two GWAS / QTL signals share the s...
Bioconductor package discovery, workflow recommendation, setup inspection, and starter code generation grounded
Score genetic compatibility across all male-female pairings in a Genomebook generation
Aggregate public target-level evidence across omics and translational sources for research triage.
Differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices with QC, PCA, and contrast testing.
Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.
Semantic search across UK Biobank's 12,000+ data fields and publications — find the right variables for your
Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant. Single client (on-demand region fetch from ...
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