Mechanism Flowchart
Generates Mermaid flowchart code and visual diagrams for pathophysiological.
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Generates Mermaid flowchart code and visual diagrams for pathophysiological.
Intelligent medical abbreviation disambiguation tool that resolves ambiguous acronyms using clinical context, specialty-specific knowledge, and document-level semantic analysis.
Comprehensive analytics tool for forecasting breakthrough therapeutic technologies by integrating multi-dimensional data sources including clinical development pipelines, intellectual property landscapes, and capital mar.
Uses analogies to explain complex medical concepts in accessible terms.
Map unstructured biomedical text to standardized ontologies (SNOMED CT.
Check for interactions between multiple medications, including severity classification and mechanism explanations.
Search FDA industry guidelines by therapeutic area or topic.
Generate 3D animation scripts and lay explanations for drug mechanisms.
Creates engaging opening statements and powerful closings for medical.
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and ...
Calls microsatellite instability from WES/WGS/targeted-panel with MSIsensor, MSIsensor-pro, MSIsensor-ct (panel-aware), MSIngs, MANTIS, MSIPanel, MSIDetect, and ngsMSI for FDA pembrolizumab MSI-H pan-tumor / Lynch syndrome / dMMR ICI biomarker. Use when stratifying ICI eligibility (Le 2015), pair...
Rank and prioritize neoantigen/epitope candidates by likely T-cell response using NeoFox feature annotation, PRIME2.0, BigMHC-IM, the Łuksza/Balachandran fitness model (agretopicity + foreignness), and pVACtools tiering. Encodes the field's hard truths that immunogenicity is the least-solved laye...
Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response...
End-to-end neoantigen discovery from somatic variants to ranked vaccine candidates. Integrates HLA typing, MHC binding prediction, pVACtools neoantigen calling, and immunogenicity scoring. Use when identifying tumor neoantigens for personalized vaccine design or checkpoint biomarkers.
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:0...
Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV and AnnotSV for semi-automated scoring. Covers the separate copy-number-loss and copy-number-gain rubrics, the five-tier classifi...
Generate professional prior authorization request letters for insurance companies with proper clinical justification and formatting.
Search PubMed/MEDLINE for biomedical literature via NCBI E-utilities API. Use when: (1) searching medical/biomedical papers, (2) finding clinical studies, (3) querying with MeSH terms, (4) retrieving abstracts by PMID. NOT for: non-biomedical papers (use arxiv-search or semantic-scholar), full-te...
Methodik zur Transformation medizinischer Arztbriefe in rechtlich verwertbare Anspruchsbegründungen gegenüber GKV und PKV im Krankenkassen-/Krankenversicherungsrecht: prüft konkret die einschlägigen Tatbestandsmerkmale, Fristen, Belege und Rechtsprechung.
Generate medical referral letters with patient summary, reason for referral.
Abrechnung Telemedizin Videosprechstunde GOÄ: prüft die einschlägigen Voraussetzungen, Dokumente, Risiken und Ausnahmen. Norm-/Quellenanker: GOÄ §§ 1-14 und Anlage, BGB Behandlungsvertrag §§ 630a ff., PKV/Beihilfe-Regelungen, Berufsrecht, aktuelle GOÄ-Reformhinweise im Goae Gebührenordnung Aerzte.
Leistungsgruppen und Qualitaetskriterien nach KHVVG: prüft Strukturmerkmale, Personal- und Geraeteanforderungen, OPS-Kodierlogik, Zuweisung durch das Land und Kooperationsmoeglichkeiten im Krankenhausrecht.
GOÄ § 1 Anwendungsbereich berufliche Leistungen: prüft die einschlägigen Voraussetzungen, Dokumente, Risiken und Ausnahmen. Norm-/Quellenanker: GOÄ §§ 1-14 und Anlage, BGB Behandlungsvertrag §§ 630a ff., PKV/Beihilfe-Regelungen, Berufsrecht, aktuelle GOÄ-Reformhinweise im Goae Gebührenordnung Aer...
Analoge Bewertung neue Verfahren Innovation: prüft die einschlägigen Voraussetzungen, Dokumente, Risiken und Ausnahmen. Norm-/Quellenanker: GOÄ §§ 1-14 und Anlage, BGB Behandlungsvertrag §§ 630a ff., PKV/Beihilfe-Regelungen, Berufsrecht, aktuelle GOÄ-Reformhinweise im Goae Gebührenordnung Aerzte.
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