SkillData & Analytics
🧬 Variant Annotation
Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking.
◈OpenClaw
By Toby ClarkOriginal project
MIT · FreeView skill
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Prompts and skills692 resources
SkillData & Analytics
SMILES Retriever
Retrieve SMILES strings from PubChem using compound names.
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Epigenetics & Drug Response
Epigenetics & Drug Response - Link epigenetics to drug response: gene regulation, variant effects, drug interactions, and expression. Use this skill for epigenetic pharmacology tasks involving get overlap region get vep hgvs get drug interactions by drug name get gene expression across cancers. C...
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
QuickGO Database Skill
Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or cellular components, find genes associated with a specific pathway/GO term, or explore the Gene Ontology hierarchy. Do not use for querying dru...
◈OpenClaw
By mkurmanOriginal project
326 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Gene-to-Drug Discovery Pipeline
Gene-to-Drug Discovery Pipeline - Full gene-to-drug pipeline: gene lookup, protein structure, binding pocket, virtual screening, and drug-likeness. Use this skill for translational medicine tasks involving get gene metadata by gene name pred protein structure esmfold run fpocket boltz binding aff...
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Gene Ontology Analysis
Gene Ontology Analysis - Analyze GO terms: ChEMBL GO slim, STRING functional enrichment, STRING annotation, and Ensembl ontology. Use this skill for functional genomics tasks involving get go slim by id get functional enrichment get functional annotation get ontology name. Combines 4 tools from 3...
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Tissue-Specific Expression Analysis
Tissue-Specific Expression Analysis - Analyze tissue-specific expression: ChEMBL tissue data, TCGA cancer expression, Ensembl gene info, and NCBI gene data. Use this skill for tissue biology tasks involving get tissue by id get gene expression across cancers get lookup symbol get gene metadata by...
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Protein Classification Analysis
Protein Classification Analysis - Classify protein: ChEMBL protein classification, UniProt entry, InterPro domains, and Ensembl biotypes. Use this skill for protein science tasks involving search protein classification get uniprotkb entry by accession query interpro get info biotypes. Combines 4 ...
◈OpenClaw
By SpectrAI-InitiativeOriginal project
380 GitHub starsApache-2.0 · FreeView skill
SkillData & Analytics
Arboreto GRN Inference
GRN inference from expression via GRNBoost2 (gradient boosting) or GENIE3 (Random Forest). Load matrix, filter by TFs, infer TF-target-importance links, save network. Dask-parallelized to single-cell scale. Core SCENIC component.
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
Guide to Pharmacology (GtoPdb) Database
Query IUPHAR/BPS Guide to Pharmacology (GtoPdb) for receptor-ligand interactions, target/ligand metadata, families, and approved drugs. Affinities (pKi/pIC50/pKd), action (Agonist/Antagonist/etc.), species, structures (SMILES/InChI). No auth. Always resolve targets via geneSymbol/accession; most ...
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
ZINC Chemical Library Database (ZINC22 / CartBlanche)
Query ZINC15/ZINC22 virtual compound libraries (1.4B compounds, 750M purchasable). Search lead/fragment/drug-like compounds by MW, logP, reactivity, or SMILES similarity; download 3D sets for docking. For bioactivity use chembl-database-bioactivity; for approved drugs use drugbank-database-access.
✳Claude Code>_Codex◈OpenClaw+1
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
UniChem Database
Cross-reference compound IDs across 20+ databases (ChEMBL, DrugBank, PubChem, ChEBI, PDB, SureChEMBL, HMDB, DrugCentral, BindingDB) via UniChem REST API. Resolve InChIKeys to source IDs, translate between source-specific IDs, find structurally related compounds by connectivity. POST with a JSON b...
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
🦖 Ancestry Decomposition PCA
Ancestry decomposition PCA against the Simons Genome Diversity Project
◈OpenClaw
By ClawBioOriginal project
MIT · FreeView skill
SkillData & Analytics
Shotgun Metagenomics Profiler
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
◈OpenClaw
By ClawBioOriginal project
MIT · FreeView skill
SkillData & Analytics
AlphaFold Database Access
Access AlphaFold DB's 200M+ predicted structures by UniProt ID. Download PDB/mmCIF, analyze pLDDT/PAE, bulk-fetch proteomes via Google Cloud. For experimental structures use PDB; for prediction use ColabFold or ESMFold.
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
CellTypist Cell Type Annotation
Automated scRNA-seq cell type annotation via pre-trained logistic regression. 45+ models: immune, gut, lung, brain, fetal, cancer microenvironments. Input normalized AnnData; outputs per-cell labels, majority-vote cluster labels, confidence scores. Use for fast, reference-backed annotation withou...
✳Claude Code>_Codex◈OpenClaw+1
By jaechang-hitsOriginal project
199 GitHub starsMIT · FreeView skill
SkillData & Analytics
dbSNP Database
Query NCBI dbSNP for SNP records by rsID, gene, or region via E-utilities and Variation Services REST API. Retrieve alleles, MAF, variant class (SNV/indel/MNV), clinical links, cross-DB IDs (ClinVar, dbVar, 1000G). Free; 3 req/sec (10 with key). For clinical pathogenicity use clinvar-database; fo...
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC0-1.0 · FreeView skill
SkillData & Analytics
GSEApy — Gene Set Enrichment Analysis in Python
GSEA and over-representation analysis (ORA) for RNA-seq and proteomics. Wraps Enrichr for ORA against MSigDB, KEGG, GO, and 200+ databases; runs preranked GSEA on ranked DE gene lists. Outputs enrichment tables and running-score plots. Use after DESeq2 or edgeR for pathway-level interpretation.
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsMIT · FreeView skill
SkillData & Analytics
Harmony Batch Correction
Harmony batch correction for scRNA-seq and other omics. Removes batch effects from PCA embeddings while preserving biology. Run after PCA, before UMAP. Scales to millions of cells. Python (harmonypy, scanpy) and R (Seurat).
✳Claude Code>_Codex◈OpenClaw+1
By jaechang-hitsOriginal project
199 GitHub starsMIT · FreeView skill
SkillData & Analytics
mouse-phenome-database
Retrieve mouse phenotype data from the Jackson Laboratory Mouse Phenome Database (MPD) via its REST API. Browse 520+ projects, look up per-project measure metadata, pull strain-level means (raw or LS-mean adjusted) and per-animal values, find measures by MP/VT ontology terms, and resolve strain n...
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
NaN-Safe Correlation Computation
Per-feature NaN-safe Spearman/Pearson correlation across many features (genes, proteins, variants) with missing values. Covers why bulk matrix shortcuts fail, correct pairwise deletion, degenerate input filtering, and large-dataset performance. Use statistical-analysis for test choice; shap-model...
✳Claude Code>_Codex◈OpenClaw+3
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
PyDESeq2 Differential Expression Analysis
Bulk RNA-seq DE with PyDESeq2: load counts, normalize, fit negative binomial models, Wald test (BH-FDR), LFC shrinkage, volcano/MA plots. Use for two-group comparisons, multi-factor designs with batch correction, multiple contrasts.
✳Claude Code>_Codex◈OpenClaw+1
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
RegulomeDB Database
Query RegulomeDB v2 GET REST API to score variants for regulatory function and retrieve overlapping evidence (TF binding, histone marks, DNase peaks, footprints, motifs, eQTLs, chromatin state). Scores range 1a (strongest) to 7 (none). Use for GWAS hit prioritization, regulatory variant annotatio...
✳Claude Code>_Codex◈OpenClaw+3
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
SkillData & Analytics
ReMap Database
Query ReMap 2022 TF ChIP-seq peak database via REST API and BED downloads. Retrieve TF peaks overlapping a region (chr:start-end), peaks near a gene, TFs by species, peaks filtered by biotype (promoter, enhancer), and BED files for a TF-cell type pair. Use for TF co-occupancy, regulatory annotati...
◈OpenClaw
By jaechang-hitsOriginal project
199 GitHub starsCC-BY-4.0 · FreeView skill
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