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Structures genetic test result interpretation with variant classification (ACMG criteria) and clinical actionability. Use when interpreting genetic results, classifying variants, or documenting genetic findings.
Structures surgical pathology reports with diagnosis, staging, margins, and prognostic markers. Use when interpreting biopsies, creating pathology reports, or documenting tissue diagnoses.
Structures drug screen interpretation with confirmation testing and clinical correlation. Use when interpreting drug screens, managing confirmatory testing, or documenting toxicology results.
Guides AUB evaluation using PALM-COEIN classification with workup algorithms. Use when evaluating abnormal bleeding, applying PALM-COEIN classification, or managing AUB workup.
Extracts and reconciles medical provider, wage-loss, and insurance/lien data from personal injury plaintiff fact sheets and initial disclosures against builder draft responses. Use when the user mentions PFS analysis, medical provider reconciliation, wage loss audit, insurance lien tracking, PI d...
Generates structured pharmaceutical regulatory compliance summaries covering FDA approval pathways, patent/IP intersections (Orange Book, Hatch-Waxman), and marketing restrictions (off-label, DTC, Anti-Kickback). Use when preparing FDA compliance overviews, submission readiness assessments, or pr...
Structured species-specific physical examination workflows and normal vital parameter reference ranges. Use when documenting or interpreting physical exam findings in animals.
Search for relevant human medical research that may inform veterinary clinical decisions when veterinary-specific evidence is lacking. Use when no species-specific evidence exists and cross-species extrapolation is considered.
Drafts jurisdiction-specific Psychiatric Advance Directives (PADs) capturing treatment preferences, agent authority, and crisis plans for psychiatric incapacity. Trigger when the user mentions psychiatric advance directive, PAD, mental health advance directive, mental health treatment declaration...
Detect drugs and substances with extreme safety variance across species where a safe dose in one species is lethal in another. CRITICAL SAFETY SKILL. Use before returning any drug information.
Drug Target Identification Pipeline - Identify drug targets for a disease by querying OpenTargets for associated targets, then retrieve detailed target info from ChEMBL and protein data from UniProt. Use this skill for drug discovery tasks involving get associated targets by disease efoId get tar...
Drug-Target Structural Biology - Integrate drug and target structure: get drug from ChEMBL, target structure from PDB, dock them, and predict ADMET. Use this skill for structural pharmacology tasks involving get drug by name retrieve protein data by pdbcode quick molecule docking pred molecule ad...
Gene-Disease Association Analysis - Analyze gene-disease associations: NCBI gene metadata, OpenTargets disease associations, TCGA expression, and Monarch phenotypes. Use this skill for medical genetics tasks involving get gene metadata by gene name get associated targets by disease efoId get gene...
Disease Protein Profiling - Profile a disease protein: UniProt data, AlphaFold structure, InterPro domains, phenotype associations from Ensembl. Use this skill for medical proteomics tasks involving query uniprot download alphafold structure query interpro get phenotype gene. Combines 4 tools fro...
Enzyme Inhibitor Design - Design enzyme inhibitor: target structure, pocket prediction, compound screening, and ADMET assessment. Use this skill for enzyme pharmacology tasks involving retrieve protein data by pdbcode pred pocket prank quick molecule docking pred molecule admet calculate mol drug...
Lead Compound Optimization - Optimize a lead compound: validate SMILES, compute drug-likeness, predict ADMET properties, and check ChEMBL bioactivity. Use this skill for medicinal chemistry tasks involving is valid smiles calculate mol drug chemistry pred molecule admet search activity. Combines ...
Search PubMed database for scientific articles and publications to retrieve biomedical literature.
Protein-Drug Interaction Profiling - Profile protein-drug interactions: protein properties, drug structure, binding affinity prediction, and interaction data. Use this skill for molecular pharmacology tasks involving calculate protein sequence properties ChemicalStructureAnalyzer boltz binding af...
Personalized Medicine Report - Generate personalized medicine report: pharmacogenomics, variant effects, drug safety, and clinical pharmacology. Use this skill for precision medicine tasks involving get pharmacogenomics info by drug name get vep hgvs get adverse reactions by drug name get clinica...
Pharmacogenomics Analysis - Pharmacogenomics analysis: FDA pharmacogenomics info, variant effects, ClinVar pathogenicity, and gene expression. Use this skill for pharmacogenomics tasks involving get pharmacogenomics info by drug name get vep hgvs clinvar search get gene expression across cancers....
Orphan Drug & Rare Disease Analysis - Analyze orphan drugs: Monarch disease phenotypes, OpenTargets targets, FDA drug data, and clinical studies. Use this skill for orphan drug development tasks involving get joint associated diseases by HPO ID list get associated targets by disease efoId get cli...
Drug Toxicity Assessment - Comprehensive toxicity assessment: FDA adverse reactions, nonclinical toxicology, carcinogenicity data, and ADMET prediction. Use this skill for toxicology tasks involving get adverse reactions by drug name get nonclinical toxicology info by drug name get carcinogenic m...
当用户需要解析、分析或理解体检报告时使用此 skill。适用于异常指标解读、疾病风险评估、核保影响分析、复查建议等场景。
当用户需要协助理赔沟通时使用此 skill。适用于理赔申请指导、与保险公司沟通话术、理赔异议处理等场景。
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